Would Muzan Kibutsuji Have Easily Defeated the Demon Slayers Without the Four Drugs?

Muzan Kibutsuji, the progenitor of demons in Demon Slayer: Kimetsu no Yaiba, was an immensely powerful being with centuries of combat experience. In the final battle, despite his overwhelming abilities, he ultimately succumbed to the combined efforts of the Demon Slayer Corps. However, a critical factor that led to his downfall was the administration of four specially crafted drugs by Tamayo. These drugs weakened him significantly, leading many fans to question: Would Muzan have easily defeated the Demon Slayers if he had not absorbed these drugs?

Understanding Muzan’s Strength and Abilities

Before diving into the impact of the four drugs, it's important to analyze Muzan’s natural power level. Muzan was nearly invincible due to his immense regenerative abilities, brute strength, high-speed movement, and ability to manipulate his body structure at will. His blood could instantly turn humans into demons, and he could create and command the Twelve Kizuki.

Additionally, Muzan’s biology allowed him to survive beheadings—an ultimate weakness for all demons except him. The only way to defeat him was complete cellular destruction by sunlight.

Even without the four drugs, Muzan was more powerful than any individual Hashira. The only reason he had not been defeated before was his ability to avoid confrontation, choosing to let his subordinates fight his battles while he remained hidden.

The Impact of the Four Drugs on Muzan

Tamayo and Shinobu Kocho created four drugs specifically to weaken Muzan. Each of these drugs played a crucial role in diminishing his ability to fight effectively:

1. Aging Acceleration Drug - This caused Muzan to age thousands of years in mere minutes, significantly draining his stamina and regeneration ability.

2. Humanization Drug - This drug forced Muzan’s demon cells to attempt to turn him back into a human, effectively attacking him from within.

3. Cell Destruction Drug - This ensured that his regeneration ability could not keep up, allowing the Demon Slayers to inflict damage that would otherwise be healed instantly.

4. Sunlight Sensitivity Drug - This made Muzan more vulnerable to sunlight, accelerating his destruction once dawn arrived.

Each of these drugs drastically weakened him, leaving him in a state where even severely wounded Demon Slayers could keep up with him in combat.

What If Muzan Hadn’t Been Weakened by the Drugs?

Had Muzan not been affected by these four drugs, the outcome of the final battle could have been drastically different. Here’s how the fight might have unfolded:

1. Muzan’s Regeneration Would Have Been Near-Perfect

One of the biggest advantages the Demon Slayers had in the final battle was that Muzan’s regeneration had been significantly slowed. If he were at full strength, he could have healed almost instantly, making it nearly impossible for any attack to deal lasting damage.

Even powerful techniques like Gyomei Himejima’s Stone Breathing or Giyu Tomioka’s Water Breathing would not have been able to do anything beyond momentarily staggering him.

2. The Demon Slayers Would Have Been Overwhelmed Instantly

Even while weakened, Muzan was able to kill multiple Demon Slayers and severely wound Hashira like Sanemi and Gyomei. If he had been at full power, he could have killed many of them outright within the first few minutes of the battle. His tentacle-like whips, which moved faster than most of them could react, would have decimated their ranks.

3. The Marked Hashira’s Abilities Would Not Have Been Enough

During the final battle, multiple Hashira awakened their Demon Slayer Marks, which enhanced their speed, strength, and endurance. However, even with these enhancements, they struggled against a weakened Muzan. If he had been at full strength, their Marks would have only delayed the inevitable.

4. Tanjiro and the Others Would Have Had No Chance

Tanjiro, the protagonist of Demon Slayer, was the strongest among the Demon Slayers, especially after mastering Sun Breathing. However, even he struggled against Muzan and only managed to survive due to the combined efforts of his comrades.

If Muzan had been at full power, Tanjiro’s Sun Breathing would not have been able to keep up for long. His stamina would have run out quickly, leaving him vulnerable to Muzan’s attacks. In this scenario, it is highly unlikely that Tanjiro would have landed any significant blows on Muzan.

5. Muzan Might Have Escaped Before Dawn

The main reason Muzan was defeated was that he was weakened to the point where he could not escape before sunrise. Without the drugs, his speed and strength would have allowed him to retreat before dawn, ensuring his survival and giving him another chance to plan his attack.

Conclusion: Would Muzan Have Won?

The answer is almost certainly yes. Without the four drugs, Muzan’s overwhelming strength, regeneration, and stamina would have ensured that he obliterated the Demon Slayer Corps before sunrise. While characters like Gyomei, Sanemi, Giyu, and Tanjiro were incredibly powerful, they still relied on Muzan’s weakened state to stand a chance.

The final battle was ultimately a war of attrition. With his regeneration slowed and his body aging thousands of years in minutes, the Demon Slayers were able to prolong the fight long enough for the sun to rise and finish the job. Without these handicaps, Muzan would have had little difficulty crushing his enemies.

This goes to show that, while the Demon Slayers fought bravely and strategically, their victory was only possible due to careful planning and the biological warfare introduced by Tamayo and Shinobu. Muzan’s raw power was, and always will be, one of the greatest threats in the Demon Slayer universe.